Migraines

Understanding migraines and CGRP

Migraine is a neurological condition, not just a bad headache. It affects millions of people and can interfere with work, family life, and everyday activities.

Research has shown that a substance called CGRP (calcitonin gene-related peptide) plays an important role in how migraines develop. Understanding this helps explain why certain migraine treatments work and why some people experience repeated attacks.

What is CGRP and how does it affect migraines?

CGRP is a protein involved in transmitting pain signals in the nervous system. During a migraine attack, CGRP levels increase in the brain. This can cause blood vessels to widen and lead to inflammation, which contributes to migraine symptoms.

When CGRP levels rise, people may experience an intense headache along with other migraine symptoms such as sensitivity to light and sound, nausea, or vomiting.

Some people also experience additional symptoms, including dizziness or vertigo, difficulty speaking, confusion, mood changes, or extreme tiredness.

If you have frequent or severe headaches with these symptoms, it’s important to seek medical advice. Migraine treatments are available and can help manage symptoms.

Common migraine triggers

While CGRP is involved in migraine attacks, migraines are often triggered by a combination of factors. Triggers vary from person to person.

Common migraine triggers include missed meals, dehydration, too much caffeine or alcohol, bright or flickering lights, loud noises, strong smells, hormonal changes such as periods or menopause, stress, anxiety, poor sleep, or changes in sleep routine. Some medicines, including certain hormonal treatments, can also play a role.

Keeping a migraine diary can help you identify personal triggers and patterns, making migraines easier to manage over time.

Migraine treatment and support at Nashi Pharmacy

Migraine treatment depends on your symptoms, how often migraines occur, and how severe they are.

Through the Nashi Pharmacy online clinic, you can complete a confidential consultation to review your symptoms and migraine history. A clinician will assess your information and advise on suitable migraine treatment options if appropriate.

If your symptoms suggest a more complex condition or need specialist care, you’ll be advised to speak to your GP or a specialist.